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Course catalogue

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Academic Programme

Implemented from September 2025

Bionanotechnology (3 ECTS)

Content
  1. Bionanotechnology: historical perspective; fundamental concepts; impact in the society.
  2. Interaction of nanomaterials with biological molecules and cells: most common nanomaterials in bionanotechnology and their properties; key factors for the interaction between nanomaterials and cells; chemical modification of nanomaterials for interaction with biological systems; methods to study the interaction between nanomaterials and biomolecules or cells.
  3. Bionanotechnology: Biosensors; drug and gene delivery; Nanotheragnostics; Nanotoxicology; Biosurfaces analysis by surface probe microscopy (SPM); Nanomachines; Molecular printing of proteins.
Aims

The main objective of the course is to provide advanced training in the area of bionanotechnology, with a strong focus on the relevance of the interdisciplinary role of chemistry and biology. By the end of the course, the students should be able to recognize the role of bionanotechnology as an interdisciplinary tool and to understand how to use these new tools in to solve problems in biological systems. The course starts with a discussion about the importance of nanotechnology and how nanotechnology may contribute to the development of new technological solutions (theme 1). Then, some relevant properties of nanomaterials are addressed (theme 2), with special focus in applications in bionanotechnology. Bionanotechnology is then used as a scaffold to consolidate and develop the previous topics in specific questions that will be addressed as case studies (theme 3). In this part, the students will develop their critical thinking and analytical skills by applying the previously addressed principles.

Recommended Books
  • de la Fuente J. M.; V. Grazu V., Eds. (2012), Nanobiotechnology: Inorganic nanoparticles; Frontiers of Nanoscience, Vol. 4 vs Organic Nanoparticles, Elsevier.
  • Jarvis, C., Ed. (2018) Nanobiotechnology: an Introduction; Larssen & Keller.
  • Goswami, A.; Choudhury, S. R., Eds (2017) Nanobiotechnology: Basic and Applied Aspects; Union Bridge.
  • Niemeyer, C.M.; Mirkin, C.A., Eds. (2004). Nanobiotechnology: Concepts, Applications and Perspectives; Weinheim, Alemanha: Wiley-VCH.
  • Mirkin, C.A., Niemeyer, C.M., Eds. (2007). Nanobiotechnology II: More Concepts and Applications; Weinheim, Alemanha: Wiley-VCH.
  • Goodsell, D.S. (2012) Bionanotechnology: Lessons from Nature, Hoboken, NJ, USA: Wiley-Liss.

 

Teaching Staff

Eulália Pereira (responsible)

Hours

21 h (lectures + theoretical-practical classes)

Grading System

An integrated approach is followed, including theoretical classes about the main concepts, case studies relevant to the syllabus, followed by a component of active learning, in group or individually, that allows that the students explore and apply the concepts learned. These components are:

  1. Oral presentation of scientific articles about selected subjects;
  2. Debate about the ethical and societal impact of bionanotechnology;
  3. Writing an abstract for a scientific paper;
  4. Oral presentation of an innovative project using bionanotechnology.

The evaluation is based in these components, with the following weights: 1) 30%; 2) 20%; 3) 20%; 4) 30%.